Selective enzymatic esterification of lignin model compounds in the ball mill

• Ulla Weißbach,
• Saumya Dabral,
• Laure Konnert,
• Carsten Bolm and
• José G. Hernández

Beilstein J. Org. Chem. 2017, 13, 1788–1795, doi:10.3762/bjoc.13.173

• proved beneficial and both the long-chain fatty ester dilignol derivatives 6b,c were isolated in good yields (Scheme 4). Conclusion In summary, the lipase-catalyzed esterification of lignin model compounds under mechanochemical conditions was investigated. Experimental parameters such as milling time

A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes

• Yong Miao,
• Florence Djedaïni-Pilard and
• Véronique Bonnet

Beilstein J. Org. Chem. 2014, 10, 2654–2657, doi:10.3762/bjoc.10.278

• with a promising yield. Keywords: fatty ester; green chemistry; lipase; mono-substituted amphiphilic cyclodextrins; peptide Coupling; solvent-free medium; transesterification; Introduction Cyclodextrins (CDs) are sustainable compounds which are particularly interesting in the frame of pharmaceutical

• transesterification with the corresponding fatty ester, which may lead to bicatenar amphiphilic CDs. At the same time, the two remaining secondary alcohols might increase the solubility of the modified CD compounds. The aim of this work is to synthesize new bicatenar CDs using green methods described for the first

• ). Since the boiling point of the co-solvent (long chain fatty ester) is relatively high and the byproduct ethanol can be easily eliminated, a vacuum system can be applied in order to accelerate the reaction. A rotary evaporator allows both the reaction to be conducted under stirring whilst under vacuum at

The cross-metathesis of methyl oleate with cis-2-butene-1,4-diyl diacetate and the influence of protecting groups

• Arno Behr and
• Jessica Pérez Gomes

Beilstein J. Org. Chem. 2011, 7, 1–8, doi:10.3762/bjoc.7.1

• catalyst loading of [Ru]-7 in a range of 0.1 and 1.5 mol %. Cross-metathesis selectivity was increased by 60% to 67%. With a catalyst loading of 1.5 mol % of [Ru]-7, a nearly quantitative conversion of unsaturated fatty ester 1 was achievable (Table 2, entry 4). Moreover, the undesired self-metathesis